Speaker

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Kevin Gardner, PhD

Virginia Lazenby O’Hara Chair in Biochemistry and W.W. Caruth Jr. Scholar in Biomedical Research, The University of Texas Southwestern Medical Center at Dallas

Dr. Gardner is the Virginia Lazenby O’Hara Chair in Biochemistry and W.W. Caruth Jr. Scholar in Biomedical Research at the UT Southwestern Medical Center in Dallas.  Dr. Gardner joined the UT Southwestern faculty in 1998 after Ph.D. (Yale, 1995) and postdoctoral (Univ. Toronto with Lewis Kay, 1998) studies in structural biology, specializing in solution nuclear magnetic resonance applications to protein structure.  Working together with collaborating biochemistry and chemistry groups, his laboratory seeks to probe the signaling mechanisms of proteins used by cells to sense and respond to the environment around them.  This research aims to decipher how proteins use common sensory mechanisms despite tremendous diversity in their functions and biological settings – for example, revealing how a cancer-related transcription factor in human cells senses natural metabolites similarly to a photosensory protein looking for blue light within marine bacteria.  Such studies lay the foundation for both understanding the natural regulation of these systems and artificially controlling them.